smith nicholas isaac

Nicholas Isaac SMITH



Ph.D. (Engineering/Applied Physics) Osaka University
B.Sc., honours (Physics, 1st class Hons) University of Sydney
B.Sc. (Physics/Pure Mathematics) University of Sydney


Specially Appointed Associate professor, Immunology Frontier Research Center, Osaka University
Specially Appointed Lecturer, Immunology Frontier Research Center, Osaka University
Designated Lecturer, Photonics Center, Osaka University
Assistant Professor, Dept Frontier Biosciences, Osaka University
JST Post-doctoral fellowship at Osaka University



Y. Kumamoto, N. I. Smith, K. Fujita, J. Ando, S. Kawata
"Light-Based Techniques for Future Pacemaker Technology" in Pacemakers,
Theory and Applications - (Intech Publishing, in press)
N. Smith, K. Fujita, S. Kawano, M. Yamanaka, and S. Kawata
"Nonlinear fluorescence imaging by saturated excitation"
in Nanoscopy Multidimensional Optical Fluorescence Microscopy - (A. Diaspro Ed. Taylor & Francis, Florida, 2010)
N. Smith, S. Iwanaga, H. Niioka, K. Fujita, and S. Kawata,
"Subcellular effects of femtosecond laser irradiation" in Nano Biophotonics - (H. Masuhara, S. Kawata, and F. Tokunaga, Ed. Elsevier B.V., Amsterdam, 2007)


A. J. Hobro, A. Konishi, C. Coban and N. I. Smiith,
"Raman spectroscopic analysis of malaria disease progression via blood and plasma samples",
Analyst (2013), in press
D. Pissuwan, Y. Kumagai and N. Smith,
"Effect of surface-modified gold nanorods on inflammatory cytokine response in macrophage cells",
Part. Part. Syst. Charact. (2013), in press.
Y. Cotte, F. Toy, P. Jourdain, N. Pavillon, D. Boss, P. Magistretti, P. Marquet and C. Depeursinge,
"Marker-free Phase Nanoscopy",
Nature Photon. 7(2), pp. 113-117 (2013)
N. Pavillon, K. Bando, K. Fujita and N. I. Smith,
"Feature-based recognition of Surface-enhanced Raman spectra for biological targets",
J. Biophotonics (2012), in press
Y. Kumamoto, A. Taguchi, N. I. Smith and S. Kawata,
"Deep ultraviolet resonant Raman imaging of a cell",
J. Biomed. Opt. 17(7), pp. 076001-1-076001-4 (2012)
K. Lau, A. Hobro, T. Smith, T. Thurston and B. Lendl,
"Label-free non-destructive in situ biochemical analysis of nematode Steinernema kraussei using FPA-FTIR and Raman spectroscopic imaging",
Vib. Spectrosc. 60, pp. 34-42 (2012)
R. Kurihara, D. Pissuwan, T. Mori, Y. Katayama and T. Niidome, "
Biodistribution and Tumor Localization of PEG-modified Dendritic Poly(L-lysine) Oligonucleotide Complexes",
J. Biomat. Sci-Polym. E. 23, pp. 2369--2380 (2012)
K. Nose, D. Pissuwan, M. Goto, Y. Katayama and T. Niidome,
"Gold nanorods in an oil-base formulation for transdermal treatment of Type 1 diabetes in mice",
Nanoscale 4, pp. 3776-3780 (2012)
T. Niidome, A. Shiotani, Y. Akiyama, A. Ohga, K. Nose, D. Pissuwan and Y. Niidome,
"Theragnostic approaches using gold nanorods and near infrared light",
Yakugaku Zasshi (J. Pharmaceut. Soc. Japan) 130(12), pp. 1671-1677 (2012)
M. Okada, N. I. Smith, A. Palonpon, H. Endo, S. Kawata, M. Sodeoka and K. Fujita,
"Label-free Raman observation of cytochrome c dynamics during apoptosis",
P. Natl. Acad. Sci. USA 109(1), pp. 28-32 (2012)
A. Hobro, S. Abdali and E. Blanch,
"SERS study of methylated and nonmethylated ribonucleosides and the effect of aggregating agents",
J. Raman Spectrosc. 43(2), pp. 187-195 (2012)
M. Rafique, S. Bashir, W. Husinsky, A. Hobro and B. Lendl,
"Surface analysis correlated with the Raman measurements of a femtosecond laser irradiated Ca F2",
Appl. Surf. Sci. 258(7), pp. 3178-3183 (2012)
N. Pavillon, J. Kühn, C. Moratal, P. Jourdain, C. Depeursinge, P. J. Magistretti and P. Marquet,
"Early Cell Death Detection with Digital Holographic Microscopy",
PLoS ONE 7(1), pp. e30912 (2012)
E. Shaffer, N. Pavillon and C. Depeursinge,
"Single-shot, simultaneous incoherent and holographic microscopy",
J. Microsc. 245(1), pp. 49-62 (2012)
J. Ando, K. Fujita, N. Smith and S. Kawata,
"Dynamic SERS imaging of cellular transport pathways with endocytosed gold nanoparticles",
Nano Lett. 11(12), pp. 5344-5348 (2011)
M. Honda, Y. Saito, N. Smith, K. Fujita and S. Kawata,
"Nanoscale heating of laser irradiated single gold nanoparticles in liquid",
Opt. Express 19(13), pp. 12375-12383 (2011)
S. Kawano, N. Smith, M. Yamanaka, S. Kawata and K. Fujita,
"Determination of the expanded optical transfer function in saturated excitation imaging and high harmonic demodulation",
Appl. Phys. Express 4(4), pp. 042401 (2011)
Y. Kumamoto, A. Taguchi, N. I. Smith and S. Kawata,
"Deep UV resonant Raman spectroscopy for photodamage characterization in cells",
Biomed. Opt. Express 2(4), pp. 927-936 (2011)
M. Yamanaka, Y.-K. Tzeng, S. Kawano, N. I. Smith, S. Kawata, H.-C. Chang and K. Fujita,
"SAX microscopy with fluorescent nanodiamond probes for high-resolution fluorescence imaging",
Biomed. Opt. Express 2(7), pp. 1946-1954 (2011)
M.-L. Zheng, K. Fujita, W.-Q. Chen, N. Smith, X.-M. Duan and S. Kawata,
"Comparison of staining selectivity for subcellular structures by carbazole-based cyanine probes in nonlinear optical microscopy",
ChemBioChem 12(1), pp. 52-55 (2011)
D. Pissuwan, T. Niidome and M. Cortie,
"The forthcoming applications of gold nanoparticles in drug and gene delivery systems",
J. Control. Release 149(1), pp. 65-71 (2011)
D. Pissuwan, K. Nose, R. Kurihara, K. Kaneko, Y. Tahara, N. Kamiya, M. Goto, Y. Katayama and T. Niidome,
"A solid-in-oil dispersion of gold nanorods can enhance transdermal protein delivery and skin vaccination",
Small 7(2), pp. 215-220 (2011)
P. Jourdain, N. Pavillon, C. Moratal, D. Boss, B. Rappaz, C. Depeursinge, P. Marquet and P. J. Magistretti,
"Determination of transmembrane water fluxes in neurons elicited by glutamate ionotropic receptors and by the co-transporters KCC2 and NKCC1: a Digital Holographic Microscopy study",
J. Neurosci. 31(33), pp. 11846-11854 (2011)
C. S. Seelamantula, N. Pavillon, C. Depeursinge and M. Unser,
"Exact Complex-Wave Reconstruction in Digital Holography",
J. Opt. Soc. Am. A 28(6), pp. 983-992 (2011)
A. Hobro and B. Lendl,
"Fourier-transform mid-infrared FPA imaging of a complex multicellular nematode",
Vib. Spectrosc. 57(2), pp. 213-219 (2011)
B. Zachhuber, G. Ramer, A. Hobro, E. Chrysostom and B. Lendl,
"Stand-off Raman spectroscopy: A powerful technique for qualitative and quantitative analysis of inorganic and organic compounds including explosives"
Anal. Bioanal. Chem. 400(8), pp. 2439-2447 (2011)