Satoshi Uematsu

植松 智|Satoshi Uematsu

大阪大学研究者総覧

学歴

1997
大阪市立大学医学部 卒業
2004
大阪大学医学系研究科 その他

職歴

1997
大阪市立大学第2内科研修医

業績

主な論文

Fujimoto K, Karuppuchamy T, Takemura N, Shimohigoshi M, Machida T, Haseda Y, Aoshi T, Ishii KJ, Akira S, Uematsu S. A New Subset of CD103+CD8{alpha}+ Dendritic Cells in the Small Intestine Expresses TLR3, TLR7, and TLR9 and Induces Th1 Response and CTL Activity. J Immunol. 2011 Jun 1;186(11):6287-95.
Uematsu S*, Fujimoto K*, Jang MH, Yang BG, Jung YJ, Nishiyama M, Sato S, Tsujimura T, Yamamoto M, Yokota Y, Kiyono H, Miyasaka M, Ishii KJ, Akira S. Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5. Nat Immunol. 2008 Jul;9(7):769-76. *equal contribution
Uematsu S, Kaisho T, Tanaka T, Matsumoto M, Yamakami M, Omori H, Yamamoto M, Yoshimori T, Akira S. The C/EBPbeta Isoform 34-kDa LAP Is Responsible for NF-IL-6-Mediated Gene Induction in Activated Macrophages, but Is Not Essential for Intracellular Bacteria Killing. J Immunol. 2007 Oct 15;179(8):5378-86.
Uematsu S*, Jang MH*, Chevrier N, Guo Z, Kumagai Y, Yamamoto M, Kato H, Sougawa N, Matsui H, Kuwata H, Hemmi H, Coban C, Kawai T, Ishii KJ, Takeuchi O, Miyasaka M, Takeda K, Akira S. Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c(+) lamina propria cells. Nat Immunol. 2006 Aug;7(8):868-74. *equal contribution
Uematsu S, Sato S, Yamamoto M, Hirotani T, Kato H, Takeshita F, Matsuda M, Coban C, Ishii KJ, Kawai T, Takeuchi O, Akira S. Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction. J Exp Med. 2005 Mar 21;201(6):915-23.
Uematsu S, Matsumoto M, Takeda K, Akira S. Lipopolysaccharide-Dependent Prostaglandin E(2) Production Is Regulated by the Glutathione-Dependent Prostaglandin E(2) Synthase Gene Induced by the Toll-Like Receptor 4/MyD88/NF-IL6 Pathway. J Immunol. 2002 Jun 1;168(11):5811-5816.

英文総説

Uematsu S, Akira S. Immune responses of TLR5(+) lamina propria dendritic cells in enterobacterial infection. J Gastroenterol. 2009;44(8):803-11.
Uematsu S, Akira S. Toll-Like Receptors (TLRs) and Their Ligands. Handb Exp Pharmacol. 2008;183:1-20.
Uematsu S, Akira S. Toll-like Receptors and Type I Interferons. J Biol Chem. 2007 May 25;282(21):15319-23.
Uematsu S, Akira S. Toll-like receptors and innate immunity. J Mol Med. 2006 Sep;84(9):712-25.
Uematsu S, Akira S. The role of Toll-like receptors in immune disorders. Expert Opin Biol Ther. 2006 Mar;6(3):203-14.
Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell. 2006 Feb 24;124(4):783-801.

受賞・表彰

2009
第4回免疫学会奨励賞(2009年12月)