The article regarding development of gout caused by activated innate immunity has been published.

Prof. Shizuo Akira, Core Researcher of the AKIRA Project, Specially Appointed Assoc. Prof. Tatsuya Saitoh, Sub-Project Member of the AKIRA Project and their co-workers have published an article about development of severe inflammatory disease such as gout caused by activated innate immunity in Nature Immunology.

This paper is an outcome of the AKIRA Project, FIRST Program.

〔The article published〕

Takuma Misawa, Michihiro Takahama,Tatsuya Kozaki, Hanna Lee, Jian Zou, Tatsuya Saitoh and Shizuo Akira:
Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome,
Nature Immunology, Vol.14, pp.454-460, 2013.


The article posting site (Nature Immunology).

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